![]() Discontinue piperacillin and tazobactam for injection if a reaction occurs. Serious hypersensitivity reactions (anaphylactic/anaphylactoid) reactions have been reported in patients receiving piperacillin and tazobactam for injection.See the full prescribing information for the preparation and administration instructions for piperacillin and tazobactam for injection, USP single-dose vials.Co-administration via Y-site can be done under certain conditions. Piperacillin and tazobactam for injection, USP and aminoglycosides should be reconstituted, diluted, and administered separately.Administer piperacillin and tazobactam for injection, USP by intravenous infusion over 30 minutes to both adult and pediatric patients (.Recommended Dosage of Piperacillin and Tazobactam for Injection for Pediatric Patients 2 months of Age and Older, Weighing up to 40 Kg and With Normal Renal Function Ageĩ0 mg/kg (80 mg piperacillin/10 mg tazobactam)ġ12.5 mg/kg (100 mg piperacillin/12.5 mg tazobactam) ![]() Pediatric Patients by Indication and Age: See.Adult Patients with Renal Impairment: Dosage in patients with renal impairment (creatinine clearance ≤40 mL/min) and dialysis patients should be reduced, based on the degree of renal impairment.Adult Patients with Nosocomial Pneumonia: Initial presumptive treatment of patients with nosocomial pneumonia should start with piperacillin and tazobactam for injection, USP at a dosage of 4.5 g every six hours plus an aminoglycoside, totaling 18.0 g (16.0 g piperacillin/2.0 g tazobactam).Adult Patients With Indications Other Than Nosocomial Pneumonia The usual daily dosage of piperacillin and tazobactam for injection, USP for adults is 3.375 g every six hours totaling 13.5 g (12.0 g piperacillin/1.5 g tazobactam).
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